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Bristol Myers Squibb Stock Rises After Solid Earnings. But These Problems Remain.

Oct 30, 2025 07:32:00 -0400 by Mackenzie Tatananni | #Biotech and Pharma #Earnings Report

Bristol Myers Squibb said generics continued to have an impact on its legacy portfolio, which includes drugs such as its blockbuster blood thinner Eliquis. (George Frey/Bloomberg)

Key Points

Bristol Myers Squibb hiked its full-year guidance on the back of a strong third quarter underlined by demand for drugs within its growth portfolio.

Adjusted earnings of $1.63 a share a share came in above the $1.51 consensus among analysts polled by FactSet. Total revenue grew 3% to $12.2 billion, topping Wall Street’s calls for $11.8 billion.

The pharmaceutical giant raised its full-year revenue guidance to a range of $47.5 billion to $48 billion from a previous forecast of $46.5 billion to $47.5 billion. Bristol Myers now sees adjusted earnings between $6.40 and $6.60 a share, versus a previous range of $6.35 to $6.65 a share.

Revenue for the company’s growth portfolio climbed 17% to $6.9 billion, corrected for foreign exchange effects. Bristol Myers attributed the increase to demand for treatments within its immuno-oncology portfolio and medications such as Reblozyl, Camzyos, and Breyanzi.

There were some blemishes on an otherwise solid print. Legacy portfolio revenue fell 13% to $5.4 billion. While demand increased for Eliquis, the company’s blockbuster blood thinner, this was “more than offset” by the continued impact of generics, or copies of the company’s brand-name drugs sold by competitors.

Shares rose after the earnings report, 1.8% higher in the premarket session. Pharma peers Johnson & Johnson and Merck were flat and down 3%, respectively. Merck also reported third-quarter earnings on Thursday.

Earlier this month, Bristol Myers announced it had agreed to pay $1.5 billion to acquire Orbital Therapeutics, an early-stage biotechnology company that specializes in RNA-based medicines.

Write to Mackenzie Tatananni at mackenzie.tatananni@barrons.com