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U.S. Markets Closed Down Wednesday; D-Wave Quantum Took Biggest Hit

Oct 22, 2025 16:10:00 -0400 | #Markets

U.S. stock indexes fell Wednesday with the falling 0.93%. Meanwhile, the declined 0.71%, and the dropped 0.53%.

The , which focuses on small-cap stocks, fell 1.42%, while the Cboe Volatility Index was up 4.20%.

Among companies with at least $10 billion in market value, D-Wave Quantum Inc. (QBTS) posted the largest decline during the session, plunging 15.16%, followed by Oklo Inc. (OKLO) shares, which plunged 13.96%. Shares of Galaxy Digital Inc. (GLXY) plunged 12.88%.

Intuitive Surgical Inc. (ISRG), was the biggest leader, jumping 13.89%, and Avery Dennison Corp. (AVY) gained 9.48%. Halliburton Co. (HAL) rounded out the top three leaders on Wednesday, with shares increasing 4.32%.

In commodities news, Brent crude oil futures were up 1.33%, and gold futures were up 0.25%. rose 0.07% to $107,937.

The 10-Year Treasury yield fell to 3.954%.

Stock indexes in Asia were down, with Japan’s NIKKEI 225 Index dropping 0.02% and China’s Shanghai Composite Index falling 0.07%.

In Europe, indexes were mixed, with the STOXX Europe 600 Index flat and the FTSE 100 Index increasing 0.93% from the previous close.

U.S. stock markets close for trading at 4 p.m. ET. For regular updates on the trading day, visit Barron’s.

Editor’s Note: This story was auto-generated by Automated Insights, an automation technology provider, using data from Dow Jones and FactSet. See our market data terms of use.