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U.S. Markets Moved Upward Wednesday; Exact Sciences Topped Leaders

Nov 19, 2025 16:10:00 -0500 | #Markets

U.S. stock indexes moved upward Wednesday with the gaining 0.59%. Meanwhile, the gained 0.38%, and the increased 0.10%.

The , which focuses on small-cap stocks, increased 0.19%, while the Cboe Volatility Index was down 5.27%.

Among companies with at least $10 billion in market value, Exact Sciences Corp. (EXAS), was the biggest leader during the session, soaring 23.68%, and Lumentum Holdings Inc. (LITE) rose 8.69%. MP Materials Corp. (MP) rounded out the top three leaders on Wednesday, with shares gaining 8.61%.

Eversource Energy (ES) posted the largest decline, tumbling 12.46%, followed by AECOM (ACM) shares, which plunged 11.10%. Shares of Strategy Inc. (MSTR) declined 9.82%.

In commodities news, Brent crude oil futures were up 0.08%, and gold futures were up 0.20%. was up 0.15% to $89,578.

The 10-Year Treasury yield rose to 4.133%.

Stock indexes in Asia were mixed, with Japan’s NIKKEI 225 Index down 0.34% and China’s Shanghai Composite Index up 0.18%.

In Europe, indexes were mixed, with the STOXX Europe 600 Index flat and the FTSE 100 Index dropping 0.47% from the previous close.

U.S. stock markets close for trading at 4 p.m. ET. For regular updates on the trading day, visit Barron’s.

Editor’s Note: This story was auto-generated by Automated Insights, an automation technology provider, using data from Dow Jones and FactSet. See our market data terms of use.